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| Poster session: Molecular targeting / Gene Therapy |
| Date: | Friday, 7 June 2002 |
| Time: | 17:15-18:45 |
| Room: | |
| 17:15-18:45 |
0449 |
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mRNA electroporation of human monocytes followed by rapid in vitro differentiation leads to highly stimulatory mature antigen-loaded dendritic cells
P. Ponsaerts, G. Van den Bosch, N. Cools, A. Van Driessche, G. Nijs, M. Lenjou, D.R. Van Bockstaele, Z.N. Berneman, V.F.I. Van Tendeloo (Edegem (antwerp), Belgium)
| 17:15-18:45 |
0450 |
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mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation
P. Ponsaerts, V.F.I. van Tendeloo, N. Cools, A. Van Driessche, F. Lardon, G. Nijs, M. Lenjou, G. Mertens, C. van Broeckhoven, D.R. van Bockstaele, Z.N. Berneman (Edegem (antwerp), Belgium)
| 17:15-18:45 |
0451 |
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THE USE OF ATRA AND TRAIL IN COMBINATION FOR THE TREATMENT OF ACUTE MYELOID LEUKAEMIA
A. Awan, K. Tobal, J. Adams, J. A. Liu Yin (Manchester, United Kingdom)
| 17:15-18:45 |
0452 |
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TARGETING SURVIVIN WITH DNAZYMES EFFICIENTLY CLEAVES ITS TRANSCRIPTS AND INDUCES APOPTOSIS IN MYELOID LEUKAEMIAS
K. Tobal, M. Kabuli, R. Brooke, J.A. Liu Yin, J.A. Liu Yin (Manchester, United Kingdom)
| 17:15-18:45 |
0453 |
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DNAZYMES TARGETING THE XIAP CLEAVE ITS TRANSCRIPT AND INDUCES APOPTOSIS IN MYELOID LEUKAEMIAS
K. Tobal, M. Kabuli, R. Brooke, J.A. Liu Yin (Manchester, United Kingdom)
| 17:15-18:45 |
0454 |
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Inhibition of ETO mediated repression of gene expression by interfering peptides
S. Schüle, D. Hildebrand, M. Grez (Frankfurt/ Main, Germany)
| 17:15-18:45 |
0455 |
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ANTISENSE DOWNREGULATION OF GENE EXPRESSION IN CHRONIC MYELOID LEUKEMIA; DELIVERY COUNTS
M. Lawler, L. O Connor, S. McElwaine, K. Gately, D. Hollywood, T. Cotter, S.R. McCann, M. Lawler (Dublin, Ireland)
| 17:15-18:45 |
0456 |
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Chemoprotection of marrow-repopulating human peripheral blood progenitor cells transduced with the human multidrug resistance-1 gene
S. Fruehauf, B. Schiedlmeier, A.L. Schilz, S. Naundorf, K. Kühlcke, C. Baum, W.J. Zeller, H.G. Eckert, S. Laufs (Heidelberg, Germany)
| 17:15-18:45 |
0457 |
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DEVELOPMENT OF AN IMPROVED PROTOCOL TO TRANSDUCE B CELL PRECURSOR ALL BLASTS WITH LENTIVIRAL VECTORS DRIVING HIGH EXPRESSION OF A TRANSGENE
M. Introna, M. Bonamino, E. Biagi, G. Gaipa, E. Todisco, J. Golay, A. Biondi (Milano, Italy)
| 17:15-18:45 |
0458 |
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PML/RAR `alpha'-TARGETING DNAZYMES SUPRESS PROLIFERATION AND INDUCE APOPTOSIS IN APL CELLS
A. Kabuli, R. Brooke, K. Tobal, J.A. Liu Yin (Manchester, United Kingdom)
| 17:15-18:45 |
0459 |
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TARGETING OF THE OLIGOMERIZATION INTERFACE OF ABL-FUSION PROTEINS INFLUENCES SENSITIVITY TO STI571
T. Beissert, D. Hoelzer, O.G. Ottmann, M. and Ruthardt (Frankfurt, Germany)
| 17:15-18:45 |
0460 |
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Adenovirally Transduced Dendritic Cells Induce Bispecific CTL Responses against both Adenovirus and CMVpp65 or EBV EBNA3C Protein: A Novel Approach for Immunotherapy
Y.H. Hamel, N.W.B. Blake, S.G. Gabrielsson, T.H. Haigh, K.J. Joos, A.B.R. Rickinson, A.F. Fischer, M.C.C. Cavazzana-Calvo (Paris, France)
| 17:15-18:45 |
0461 |
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Correction of the Immunodeficiency and Lack of Toxicity after Retroviral-Mediated
RAG-2 Gene Transfer in RAG-2 Deficient Mice
F. Yates, M Malassis-Séris, D.B. Kohn, O. Danos, A. Fischer, J.P. de Villartay, M. Cavazzana-Calvo (Paris, France)
| 17:15-18:45 |
0462 |
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ADENYLOSUCCINAT-SYNTHEASE AND ADENOSINE KINASE INHIBITION AS THERAPEUTIC TARGETS IN MTAP-NEGATIVE MALIGNANCIES
M.S. Schmid, H. Ruff, K. Lehmann, H. Cottam, H. Doehner (Ulm, Germany)
| 17:15-18:45 |
0463 |
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DOWN MODULATION OF SHP2 TYROSINE PHOSPHATASE AS EARLY EVENT OF IN VITRO RESISTANCE TO STI571
C. Quintarelli, R. Di Noto, G. Muccioli Casadei, A. Sparacino, M. Bartiromo, B. Izzo, M. Intrieri, D. Alberti, G. Rosti, M. Baccarani, G. Saglio, F. Pane, F. Salvatore (Napoli, Italy)
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