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| Chronic Lymphocytic Leukemia: Biology ZAP |
| Date: | Sunday, June 13 2004 |
| Time: | 11:00-12:00 |
| Room: | Room H, Geneva Palexpo |
| 11:00-11:15 |
636 |
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ZAP-70 PROTEIN TYROSINE KINASE IS AN INDEPENDENT MARKER OF DISEASE PROGRESSION IN B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA
G. Del Poeta, M.I. Del Principe, L. Maurillo, M. Irno Consalvo, A. Venditti, F. Buccisano, R. Marini, R. Bomben, M. Degan, M. Dal Bo, M.C. Cox, P. Panetta, D. Piccioni, G. Suppo, M. Cecconi, V. Gattei, S. Amadori (Roma, Italy)
| 11:15-11:30 |
637 |
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CXCL12 INDUCES ACTIN POLYMERISATION AND SUSTAINED ERK ACTIVATION IN B-CLL CELLS EXPRESSING ZAP-70
S.J. Richardson, J.A. Copplestone, A.G. Prentice (Plymouth, United Kingdom)
| 11:30-11:45 |
638 |
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ZAP-70 PROTEIN EXPRESSION IS NEGATIVE, AND THE GENE PROMOTER REGION IS METHYLATED, IN MOST CASES OF MCL AND SLVL, AND DOES NOT CORRELATE WITH IGVH GENE MUTATIONAL STATUS
J.A. Orchard, Z. Davis, A. Parker, R. Ibbotson, C. Feeley, D.G. Oscier (Bournemouth, United Kingdom)
| 11:45-12:00 |
639 |
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ZAP-70 EXPRESSION IN CHRONIC LYMPHOCYTIC LEUKAEMIA: CORRELATION WITH CLINICAL AND BIOLOGICAL FEATURES
I. Del Giudice, E. Matutes, A. Morilla, R. Morilla, A. Burford, S. Maravelaki, N. Osuji, K. Owusu-Ankomah, V. Brito-Babapulle, D. Catovsky (London, United Kingdom)
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